Prem Mathi Maran
CEO, Clean Green Biosystems, India
Title: A Noval method of extracting highly bio available Gallate catechins from fresh tea leaves- An Anti malarial Drug
Biography:
Dr. Prem, the founder Director and CEO of Clean Green Biosystems, Clean Green Bio Research Foundation and CRS Bio Engineering Pvt Ltd. Dr.S.Prem Mathi Maran, completed his Masters degree in Biology, Master of Philosophy in Toxicology and Doctor of Philosophy in Bio Chemistry. He is due to get his Doctor of Science in Phytochemistry. Dr.Prem is having 18 years of experience in the phytochemicals Industry. He is expert in deriving the process for herbal extraction system, phytochemicals extraction system, nutraceuticals extraction system, natural food colour extraction system and fruits and vegetable processing system. He is having expertise in the process design, process development, method development of herbal/phytochemicals/nutraceuticals/functional foods extraction system. He has developed novel methods of extracting bioactive principles from fresh herbs , fruits and vegetables. Dr. Prems other areas of expertise in HPLC and HPTLC analysis of phytochemicals, Process validation, Drug delivery system, pesticides formulation technology and biological assays. He has authored more than 25 research publications in peer reviewed journals of national and International origins. He is the associate editor of Journal of Pharmacognosy and Phytochemistry and Journal of Biotechnology and bio Engineering. He is visiting faculty in few Indian universities and handling subjects on phytochemicals extraction to M.Tech and M.S courses. Doctoral committee member in a Indian University. Technical adviser in various herbal extraction companies and phytopharmaceuticals company in India and overseas.
Abstract:
A new method , which is patented , is developed to enhance the bio availability of fresh green tea leaves to extract Gallate catechins, an anti malarial drug. The method involves use of a patented hydro dynamic system which converts the fresh tea leaves into a nano emulsion. This active catechins rich nano emulsion is filtered and clear emulsion is collected. This clear emulsion is subjected to Liquid-Liquid extraction and the catechins are isolated through a solvent phase. Then the solvent phase is dried in a molecular distillation unit and subsequently in a vacuum tray drier to get a green coloured powder. The HPLC analysis revealed that this extract is having all the 8 catechins in higher levels and its bio availability is increased to 10 fold as compared to the commercially available green tea extracts.