Natural Compounds 2021

Biography:

Solmaz masoudi completed his masterʹs degree in phyto chemistry with the title of extracting and the active ingredients of rhubarb (Rheum ribes) she has been active in the field of extraction of active substances, as well as research on polymeric substrates in the field of drug release.  She is studying in the field of shape memory polymer her Phd degree.

Abstract:

Rheum ribes L.is one of the wide rhubarb species belonging to polygonaceace. R.ribes is locally knowing as usgum or ucgum and grown mostly in eastern turkey, Lebanon and azarbaijan region of iran. Young shoots and petioles of R.ribes are used against diarrhea as well as stomachic and antiemetic while juice of some parts of the plant is used against hemorrhoids, measles, smallpox its fresh stems and petioles are consumed as vegetable, and stems are also eaten fresh, which are used as digestive and appetizer in bitlis, eastern turkey, while the roots are used to treat diabetes, hypertension, obesity, ulcer, diarrhea and expectorant. the air dried powdered stems and flowers of rheum ribes were sequentially extracted at room temperature with hexane, chloroform and methanol. separation by thin-layer chromatography was performed on silica gel 60 F₂₄₅   plates and column chromatography. the extracts were evaporated under vacuum to dryness. Hexane extract of stems of rheum was isolated by acetone/pet-ether (2:9) solvent system to 11 fractions was isolated. Chloroform extract of stems by chloroform/methanol/ethyl acetate (3:1:1) to 8 fraction was isolated and methanol extract by methanol/ethyl acetate /H₂o/acid acetic (2:1:1:0.5) to 7 fractions was isolated. hexane extract of flowers by acetone/pet-ether (3:7) 10 fractions and chloroform extract of flowers by acetone/pet-ether (1:3) to 6 fractions and methanol extract of flowers to 6 fractions was isolated. fraction 1 of chloroform stem extract by ethyl acetate/chloroform (3:4) and fraction 1 of methanol flower extract by ethyl acetate/ acid acetic/ water/ methanol (5:0.5:1:4) were isolated.  Tests were performed to identify compounds tannin, terpenoid, flavonoid, anthraquinoid, Saponoid, alkaloid, steroid of flower and stem rheum ribes L extracts. Purified compounds were identified by FT-IR spectroscopy and H¹NMR and C ¹³ NMR.